{"id":4775,"date":"2021-03-23T14:26:28","date_gmt":"2021-03-23T14:26:28","guid":{"rendered":"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/?p=4775"},"modified":"2021-03-24T11:52:44","modified_gmt":"2021-03-24T11:52:44","slug":"ovarian-cancer-the-silent-killer-if-in-doubt-get-it-checked-out","status":"publish","type":"post","link":"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2021\/03\/23\/ovarian-cancer-the-silent-killer-if-in-doubt-get-it-checked-out\/","title":{"rendered":"Ovarian Cancer: \u2018The Silent Killer\u2019 \u2013 if in doubt, get it checked out!"},"content":{"rendered":"<p><em>March is <a href=\"https:\/\/www.wsh.nhs.uk\/Staff\/Health-and-wellbeing\/Calendar\/NHS-National-Campaigns\/Ovarian-Cancer-Awareness-Month.aspx\">Ovarian Cancer Awareness Month<\/a>. To help raise awareness, <strong>Dr Rebecca Leyland, Dr Sarah Haywood-Small <\/strong>and<strong> Dr Nicola Jordan-Mahy\u00a0<\/strong>of our Cancer Research Group (Biomolecular Sciences Research Centre) have kindly provided the following information and advice . . .<\/em><\/p>\n<p>According to the latest Cancer Research UK figures, 1 in 50 UK females will be diagnosed with ovarian cancer in their lifetime. Every woman has a different experience of ovarian cancer and the incidence is strongly related to age, with the highest incidence rates being in older women. The incidence rates for ovarian cancer are projected to rise by 15% in the UK between 2014 and 2035 (statistical data from CRUK). With the current COVID-19 pandemic, cancer diagnoses have dropped critically due to people not seeking medical attention. It is crucial that you continue to see your GP if you spot any symptoms.<\/p>\n<p><strong><u>Symptoms<\/u><\/strong><\/p>\n<p>Some common symptoms, as indicated by the NHS website, include the following:<\/p>\n<ul>\n<li><strong>Feeling constantly bloated<\/strong><\/li>\n<li><strong>A swollen tummy<\/strong><\/li>\n<li><strong>Discomfort in the pelvic area<\/strong><\/li>\n<li><strong>Feeling full quickly when eating<\/strong><\/li>\n<li><strong>Needing to urinate more than often<\/strong><\/li>\n<\/ul>\n<p>These symptoms are not always easy to diagnose due to other common conditions such as irritable bowel syndrome and menstrual pains having similar symptoms. It is important to get these symptoms checked with your GP, and even more so if there is a family history of ovarian cancer. You should not feel afraid that you are wasting your GP&#8217;s time, or making a fuss. If you notice a change, or you have any of these symptoms, seek help as an early diagnosis could save your life.<\/p>\n<p><strong><u>Knowing the Risk Factors<\/u><\/strong><\/p>\n<p>The risk factors are being unfit, overweight, over 50-years-old, a family history of ovarian or breast cancer, endometriosis, smoking, using hormone replacement therapy (HRT) and exposure to asbestos.<\/p>\n<div id=\"attachment_4778\" style=\"width: 428px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2021\/03\/23\/ovarian-cancer-the-silent-killer-if-in-doubt-get-it-checked-out\/risk-factors\/#main\" rel=\"attachment wp-att-4778\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-4778\" data-attachment-id=\"4778\" data-permalink=\"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2021\/03\/23\/ovarian-cancer-the-silent-killer-if-in-doubt-get-it-checked-out\/risk-factors\/#main\" data-orig-file=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Risk-factors.jpg?fit=422%2C317&amp;ssl=1\" data-orig-size=\"422,317\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"Risk factors\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Risk factors&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Risk-factors.jpg?fit=422%2C317&amp;ssl=1\" class=\"size-full wp-image-4778\" src=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Risk-factors.jpg?resize=422%2C317&#038;ssl=1\" alt=\"Risk factors\" width=\"422\" height=\"317\" srcset=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Risk-factors.jpg?w=422&amp;ssl=1 422w, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Risk-factors.jpg?resize=300%2C225&amp;ssl=1 300w\" sizes=\"auto, (max-width: 422px) 100vw, 422px\" \/><\/a><p id=\"caption-attachment-4778\" class=\"wp-caption-text\">Risk factors<\/p><\/div>\n<p><strong><u>Prevention<\/u><\/strong><\/p>\n<p>In these challenging times, let&#8217;s triangulate some recent ideas surrounding preventive strategies, innovations in diagnosis and personalised, targeted treatments.<\/p>\n<div id=\"attachment_4779\" style=\"width: 531px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2021\/03\/23\/ovarian-cancer-the-silent-killer-if-in-doubt-get-it-checked-out\/picture7\/#main\" rel=\"attachment wp-att-4779\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-4779\" data-attachment-id=\"4779\" data-permalink=\"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2021\/03\/23\/ovarian-cancer-the-silent-killer-if-in-doubt-get-it-checked-out\/picture7\/#main\" data-orig-file=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Picture7.png?fit=525%2C295&amp;ssl=1\" data-orig-size=\"525,295\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"Picture7\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Prevention strategies&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Picture7.png?fit=525%2C295&amp;ssl=1\" class=\"wp-image-4779 size-full\" src=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Picture7.png?resize=525%2C295&#038;ssl=1\" alt=\"Prevention strategies\" width=\"525\" height=\"295\" srcset=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Picture7.png?w=525&amp;ssl=1 525w, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Picture7.png?resize=300%2C169&amp;ssl=1 300w\" sizes=\"auto, (max-width: 525px) 100vw, 525px\" \/><\/a><p id=\"caption-attachment-4779\" class=\"wp-caption-text\">Prevention strategies<\/p><\/div>\n<p><strong>TRY TO QUIT SMOKING<\/strong><\/p>\n<p>Like most diseases a healthy lifestyle can help reduce your chance of having ovarian cancer. Reducing or giving up smoking can be a first step there are many ways you can do this. A good start is to take a <a href=\"https:\/\/www.nhs.uk\/live-well\/quit-smoking\/nhs-stop-smoking-services-help-you-quit\">look at the advice on the NHS \u2018Quit Smoking\u2019 website<\/a>.<\/p>\n<p>You can also <a href=\"https:\/\/www.nhs.uk\/better-health\/quit-smoking\/?WT.mc_ID=JanQuitSmokingPPC&amp;gclid=Cj0KCQjw0caCBhCIARIsAGAfuMyDHsy6iXootX7ewU2u7rObtrdsIrXRis6d7P32u_U9IPbWLz5MypYaAiUEEALw_wcB&amp;gclsrc=aw.ds\">download the NHS Smokefree app<\/a>.<\/p>\n<p><strong>DO MORE EXERCISE<\/strong><\/p>\n<p>You can also help yourself by undertaking exercise and getting fit. This does not only help with disease prevention it also helps with your mental health, which we can all do with these days. Anything can help, even a short walk around the block. <a href=\"https:\/\/www.nhs.uk\/live-well\/exercise\">The NHS has lots of advice to help you get started<\/a>. You could take part in the <a href=\"https:\/\/www.nhs.uk\/live-well\/exercise\/?tabname=couch-to-5k\">Couch to 5k challenge<\/a>, rope a few friends in, get them to do this with you even if you have to do it virtually via Facebook, WhatsApp, etc; getting started is the hardest part, so let&#8217;s get started today!<\/p>\n<p><a href=\"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2021\/03\/23\/ovarian-cancer-the-silent-killer-if-in-doubt-get-it-checked-out\/salad-2756467_1920\/#main\" rel=\"attachment wp-att-4789\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"4789\" data-permalink=\"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2021\/03\/23\/ovarian-cancer-the-silent-killer-if-in-doubt-get-it-checked-out\/salad-2756467_1920\/#main\" data-orig-file=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/salad-2756467_1920.jpg?fit=1920%2C1281&amp;ssl=1\" data-orig-size=\"1920,1281\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"salad-2756467_1920\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/salad-2756467_1920.jpg?fit=700%2C467&amp;ssl=1\" class=\"alignleft wp-image-4789 size-medium\" src=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/salad-2756467_1920-300x200.jpg?resize=300%2C200&#038;ssl=1\" alt=\"\" width=\"300\" height=\"200\" srcset=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/salad-2756467_1920.jpg?resize=300%2C200&amp;ssl=1 300w, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/salad-2756467_1920.jpg?resize=768%2C512&amp;ssl=1 768w, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/salad-2756467_1920.jpg?resize=1024%2C683&amp;ssl=1 1024w, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/salad-2756467_1920.jpg?w=1920&amp;ssl=1 1920w, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/salad-2756467_1920.jpg?w=1400 1400w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p><strong>EAT HEALTHIER<\/strong><\/p>\n<p>Then we get on to healthy eating! The NHS has a lot of advice about eating well and we are great believers of eating the rainbow, <a href=\"https:\/\/www.nhs.uk\/live-well\/eat-well\/\">making sure your diet is balanced with a lot of colourful fruit and vegetables<\/a>, if you eat beige you feel beige. So come on, ladies, let&#8217;s change the colour of the food we feed ourselves and our families.<\/p>\n<div id=\"attachment_4782\" style=\"width: 156px\" class=\"wp-caption alignright\"><a href=\"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2021\/03\/23\/ovarian-cancer-the-silent-killer-if-in-doubt-get-it-checked-out\/nikki-jordan-mahy-2016\/#main\" rel=\"attachment wp-att-4782\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-4782\" data-attachment-id=\"4782\" data-permalink=\"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2021\/03\/23\/ovarian-cancer-the-silent-killer-if-in-doubt-get-it-checked-out\/nikki-jordan-mahy-2016\/#main\" data-orig-file=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Nikki-Jordan-Mahy-2016.jpg?fit=177%2C227&amp;ssl=1\" data-orig-size=\"177,227\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;Smith, Julie&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;1498668938&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"Nikki-Jordan-Mahy-2016\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Dr Nikki Jordan-Mahy&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Nikki-Jordan-Mahy-2016.jpg?fit=177%2C227&amp;ssl=1\" class=\"wp-image-4782 size-thumbnail\" src=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Nikki-Jordan-Mahy-2016-150x150.jpg?resize=150%2C150&#038;ssl=1\" alt=\"Dr Nikki Jordan-Mahy\" width=\"150\" height=\"150\" srcset=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Nikki-Jordan-Mahy-2016.jpg?resize=150%2C150&amp;ssl=1 150w, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Nikki-Jordan-Mahy-2016.jpg?resize=144%2C144&amp;ssl=1 144w, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Nikki-Jordan-Mahy-2016.jpg?resize=50%2C50&amp;ssl=1 50w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/a><p id=\"caption-attachment-4782\" class=\"wp-caption-text\">Dr Nikki Jordan-Mahy<\/p><\/div>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/www.shu.ac.uk\/about-us\/our-people\/staff-profiles\/nikki-jordan-mahy\">Dr Nikki Jordan-Mahy\u2019s<\/a> research focuses on polyphenols in the treatment of cancer. Interestingly, in laboratory experiments polyphenols naturally found in teas, fruit, vegetables, berries and nuts have been shown to slow down the growth and kill ovarian cancer cells (Quin <em>et al<\/em> 2020; Niedzwiecki <em>et al<\/em> 2016; Kwon 2018; Rauf <em>et al<\/em> 2018). These studies highlight the importance of a healthy diet full of fruit and vegetables, and could help to prevent and possibly one day help to treat ovarian cancer.<\/p>\n<p>&nbsp;<\/p>\n<p><strong><u>Targeted and personalised treatments<\/u><\/strong><\/p>\n<div id=\"attachment_4784\" style=\"width: 156px\" class=\"wp-caption alignright\"><a href=\"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2021\/03\/23\/ovarian-cancer-the-silent-killer-if-in-doubt-get-it-checked-out\/leyland\/#main\" rel=\"attachment wp-att-4784\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-4784\" data-attachment-id=\"4784\" data-permalink=\"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2021\/03\/23\/ovarian-cancer-the-silent-killer-if-in-doubt-get-it-checked-out\/leyland\/#main\" data-orig-file=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Leyland.jpg?fit=203%2C203&amp;ssl=1\" data-orig-size=\"203,203\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"Leyland\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Dr Rebecca Leyland&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Leyland.jpg?fit=203%2C203&amp;ssl=1\" class=\"size-thumbnail wp-image-4784\" src=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Leyland-150x150.jpg?resize=150%2C150&#038;ssl=1\" alt=\"Dr Rebecca Leyland\" width=\"150\" height=\"150\" srcset=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Leyland.jpg?resize=150%2C150&amp;ssl=1 150w, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Leyland.jpg?resize=144%2C144&amp;ssl=1 144w, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Leyland.jpg?resize=50%2C50&amp;ssl=1 50w, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Leyland.jpg?w=203&amp;ssl=1 203w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/a><p id=\"caption-attachment-4784\" class=\"wp-caption-text\">Dr Rebecca Leyland<\/p><\/div>\n<p><a href=\"https:\/\/www.shu.ac.uk\/about-us\/our-people\/staff-profiles\/rebecca-leyland\">Dr Rebecca Leyland\u2019s<\/a> research focuses on targeted cancer treatment and the use of immunotherapy drugs. Treatment of ovarian cancer depends on the type of cancer, how big it is and also the stage. Most women with ovarian cancer have surgery or chemotherapy and there are also targeted drugs which can be used to treat advanced cancer. Some examples of targeted drugs for ovarian cancer include Lynparza and Rubraca. These drugs stop a protein called Poly (ADP-ribose) polymerase from working. This protein helps to repair damaged cells, including cancer cells. There are also immunotherapy drugs in clinical trials for the treatment of ovarian cancer which are showing tremendous potential. These drugs aim to activate a person&#8217;s immune system to kill cancer.<\/p>\n<p><strong><u>New innovations in diagnosis<\/u><\/strong><\/p>\n<div id=\"attachment_4785\" style=\"width: 156px\" class=\"wp-caption alignleft\"><a href=\"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2021\/03\/23\/ovarian-cancer-the-silent-killer-if-in-doubt-get-it-checked-out\/dr-sarah-haywood-small\/#main\" rel=\"attachment wp-att-4785\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-4785\" data-attachment-id=\"4785\" data-permalink=\"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2021\/03\/23\/ovarian-cancer-the-silent-killer-if-in-doubt-get-it-checked-out\/dr-sarah-haywood-small\/#main\" data-orig-file=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Dr-Sarah-Haywood-Small.jpg?fit=200%2C186&amp;ssl=1\" data-orig-size=\"200,186\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"Dr Sarah Haywood-Small\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Dr Sarah Haywood-Small&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Dr-Sarah-Haywood-Small.jpg?fit=200%2C186&amp;ssl=1\" class=\"size-thumbnail wp-image-4785\" src=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Dr-Sarah-Haywood-Small-150x150.jpg?resize=150%2C150&#038;ssl=1\" alt=\"Dr Sarah Haywood-Small\" width=\"150\" height=\"150\" srcset=\"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Dr-Sarah-Haywood-Small.jpg?resize=150%2C150&amp;ssl=1 150w, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Dr-Sarah-Haywood-Small.jpg?resize=144%2C144&amp;ssl=1 144w, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Dr-Sarah-Haywood-Small.jpg?resize=50%2C50&amp;ssl=1 50w\" sizes=\"auto, (max-width: 150px) 100vw, 150px\" \/><\/a><p id=\"caption-attachment-4785\" class=\"wp-caption-text\">Dr Sarah Haywood-Small<\/p><\/div>\n<p>A major challenge in treating ovarian cancer is that most patients have advanced disease at initial diagnosis. The facts speak for themselves, more than a quarter of ovarian cancers cases in England are diagnosed after presenting as an emergency (latest data from CRUK). <a href=\"https:\/\/www.shu.ac.uk\/about-us\/our-people\/staff-profiles\/sarah-haywood-small\">Dr Sarah Haywood-Small\u2019s<\/a> research is in the area of breathomic research for cancer detection. A possible game changer in relation to diagnosis is the observation that exhaled breath can reveal crucial information that may indicate the presence of cancer. Simple, organic compounds can be isolated in exhaled breath as the cancer develops. Obtaining breath is non-invasive and so people can be checked regularly, therefore it follows that cancers can be detected earlier.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>In 2021, it is more important than ever to keep talking about ovarian cancer. As is said many times with cancer, if in doubt, get it checked out.<\/strong><\/p>\n<p><strong>REFERENCES:<\/strong><\/p>\n<p>Ovarian Cancer Statistics [<a href=\"https:\/\/www.cancerresearchuk.org\/health-professional\/cancer-statistics\/statistics-by-cancer-type\/ovarian-cancer\">https:\/\/www.cancerresearchuk.org\/health-professional\/cancer-statistics\/statistics-by-cancer-type\/ovarian-cancer<\/a>]. Cancer Research UK (CRUK).\u00a0 Accessed [11\/03\/2021]<\/p>\n<p>Amal, H., Shi, D. Y., Ionescu, R., Zhang, W., Hua, Q. L., Pan, Y. Y., &#8230; &amp; Haick, H. (2015). Assessment of ovarian cancer conditions from exhaled breath. International journal of cancer, 136(6), E614-E622.<\/p>\n<p>Raspagliesi, F., Bogani, G., Benedetti, S., Grassi, S., Ferla, S., &amp; Buratti, S. (2020). Detection of Ovarian Cancer through Exhaled Breath by Electronic Nose: A Prospective Study. Cancers, 12(9), 2408.<\/p>\n<p><a href=\"http:\/\/www.nhs.uk\">www.nhs.uk<\/a> National Health Service &#8211; Symptoms and Prevention<\/p>\n<p>Kwon Y. Food-derived polyphenols inhibit the growth of ovarian cancer cells irrespective of their ability to induce antioxidant responses. Heliyon. 2018 Aug 29;4(8):e00753. doi: 10.1016\/j.heliyon.2018.e00753. PMID: 30186979; PMCID: PMC6121158.<\/p>\n<p>Niedzwiecki A, Roomi MW, Kalinovsky T, Rath M. Anticancer Efficacy of Polyphenols and Their Combinations. Nutrients. 2016 Sep 9;8(9):552. doi: 10.3390\/nu8090552. PMID: 27618095; PMCID: PMC5037537.<\/p>\n<p>Rauf A, Imran M, Butt MS, Nadeem M, Peters DG, Mubarak MS. Resveratrol as an anti-cancer agent: A review. Crit Rev Food Sci Nutr. 2018 Jun 13;58(9):1428-1447. doi: 10.1080\/10408398.2016.1263597. Epub 2017 Jul 21. PMID: 28001084.<\/p>\n<p>Qin J, Fu M, Wang J, Huang F, Liu H, Huangfu M, Yu D, Liu H, Li X, Guan X, Chen X. PTEN\/AKT\/mTOR signaling mediates anticancer effects of epigallocatechin\u20113\u2011gallate in ovarian cancer. Oncol Rep. 2020 Jun;43(6):1885-1896. doi: 10.3892\/or.2020.7571. Epub 2020 Mar 31. PMID: 32236585; PMCID: PMC7160558.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>March is Ovarian Cancer Awareness Month. To help raise awareness, Dr Rebecca Leyland, Dr Sarah Haywood-Small and Dr Nicola Jordan-Mahy\u00a0of our Cancer Research Group (Biomolecular Sciences Research Centre) have kindly&hellip;<\/p>\n","protected":false},"author":3083,"featured_media":4787,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"wds_primary_category":0,"footnotes":"","jetpack_publicize_message":"Ovarian Cancer: \u2018The Silent Killer\u2019 \u2013 if in doubt, get it checked out!","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[21,104,367],"tags":[],"class_list":["post-4775","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-research","category-wellbeing"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2021\/03\/Ovarian-cancer-awareness.jpg?fit=400%2C267&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p8KEAX-1f1","jetpack-related-posts":[{"id":1711,"url":"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2018\/03\/23\/7-facts-about-ovarian-cancer-for-ovarian-cancer-awareness-month\/","url_meta":{"origin":4775,"position":0},"title":"7 facts about Ovarian Cancer for Ovarian Cancer Awareness Month","author":"Michael Cambell","date":"March 23, 2018","format":false,"excerpt":"March is Ovarian Cancer Awareness month so Gemma Burke, Senior Lecturer in Radiotherapy has kindly shared with us 7 facts about the disease in order to raise awareness. Ovarian cancer is the 6th most common cancer in women in the UK with around 20 new cases diagnosed every day, with\u2026","rel":"","context":"In &quot;Your Wellbeing&quot;","block_context":{"text":"Your Wellbeing","link":"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/category\/wellbeing\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/03\/Ovarian-Cancer-gallery.jpg?fit=1028%2C624&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/03\/Ovarian-Cancer-gallery.jpg?fit=1028%2C624&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/03\/Ovarian-Cancer-gallery.jpg?fit=1028%2C624&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/03\/Ovarian-Cancer-gallery.jpg?fit=1028%2C624&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":2840,"url":"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2018\/12\/07\/decembeard-raising-awareness-of-bowel-cancer\/","url_meta":{"origin":4775,"position":1},"title":"Decembeard- raising awareness of bowel cancer","author":"Sarah Briscoe","date":"December 7, 2018","format":false,"excerpt":"Decembeard... growing awareness of bowel cancer Following on from\u00a0Movember is\u00a0Decembeard, a campaign\u00a0run by\u00a0Bowel Cancer UK to\u00a0encourage people to grow or decorate their facial hair throughout December to support and\u00a0raise awareness of bowel cancer. Bowel cancer is the fourth most common cancer in the UK. Almost 42,000 people are diagnosed with\u2026","rel":"","context":"In &quot;News&quot;","block_context":{"text":"News","link":"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/category\/news\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/12\/Decembeard3.jpg?fit=1028%2C624&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/12\/Decembeard3.jpg?fit=1028%2C624&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/12\/Decembeard3.jpg?fit=1028%2C624&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/12\/Decembeard3.jpg?fit=1028%2C624&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":3724,"url":"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2019\/07\/31\/shu-researches-the-link-between-obesity-and-cancer\/","url_meta":{"origin":4775,"position":2},"title":"SHU researches the link between obesity and cancer","author":"Mark Greene","date":"July 31, 2019","format":false,"excerpt":"Cancer Research UK has recently launched a new campaign to raise awareness of obesity as the biggest preventable cause of cancer after smoking in the UK. More than 1 in 20 cancer cases are caused by excess weight, and one of the most common types of cancer linked to obesity\u2026","rel":"","context":"In &quot;News&quot;","block_context":{"text":"News","link":"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/category\/news\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2019\/07\/Cancer-and-obesity.jpg?fit=1028%2C624&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2019\/07\/Cancer-and-obesity.jpg?fit=1028%2C624&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2019\/07\/Cancer-and-obesity.jpg?fit=1028%2C624&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2019\/07\/Cancer-and-obesity.jpg?fit=1028%2C624&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":1122,"url":"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2018\/01\/11\/new-project-to-look-at-reducing-the-risk-of-breast-cancer-recurrence\/","url_meta":{"origin":4775,"position":3},"title":"New project to look at reducing the risk of breast cancer recurrence","author":"Michael Cambell","date":"January 11, 2018","format":false,"excerpt":"Sport scientists at Sheffield Hallam University are working on a new project that looks at helping breast cancer patients reduce the risk of the disease returning.\u00a0 Yorkshire Cancer Research has invested \u00a3238,000 into the project which is being led by Northumbria University and supported by Dr Helen Crank, a reader\u2026","rel":"","context":"In &quot;In the Headlines&quot;","block_context":{"text":"In the Headlines","link":"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/category\/news\/hwbheadlines\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/01\/breast-cancer2.jpg?fit=1028%2C624&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/01\/breast-cancer2.jpg?fit=1028%2C624&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/01\/breast-cancer2.jpg?fit=1028%2C624&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/01\/breast-cancer2.jpg?fit=1028%2C624&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":2034,"url":"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2018\/05\/25\/can-exercise-be-a-cure-for-prostate-cancer\/","url_meta":{"origin":4775,"position":4},"title":"Can exercise be a cure for prostate cancer?","author":"Sarah Briscoe","date":"May 25, 2018","format":false,"excerpt":"Dr Liam Bourke spoke to the Nigerian edition of The Guardian about his research which explores the feasibility of prescribing exercise as a treatment for men with early-stage prostate cancer.","rel":"","context":"In &quot;News&quot;","block_context":{"text":"News","link":"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/category\/news\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/06\/Prostate-Cancer-Exercise-gallery.jpg?fit=1028%2C624&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/06\/Prostate-Cancer-Exercise-gallery.jpg?fit=1028%2C624&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/06\/Prostate-Cancer-Exercise-gallery.jpg?fit=1028%2C624&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/blogs.shu.ac.uk\/hwbstaffnews\/files\/2018\/06\/Prostate-Cancer-Exercise-gallery.jpg?fit=1028%2C624&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":167,"url":"https:\/\/blogs.shu.ac.uk\/hwbstaffnews\/2017\/05\/08\/may-feature-bioscience-programmes-recognised-for-excellence\/","url_meta":{"origin":4775,"position":5},"title":"May Features &#8211; Bioscience programmes recognised for excellence;  Prostate cancer research forms new European guidelines","author":"Anna Gunn","date":"May 8, 2017","format":false,"excerpt":"Sheffield Hallam University has received Accreditation status from the Royal Society of Biology in recognition of its outstanding bioscience degree programmes. 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